Media & Investors

Ownership Summary

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Federated Global Investment Management Corp. 4,215,063 10.74 447,300 4/30/19
Wellington Management Company, LLP 3,649,897 9.30 -58,761 3/31/19
BVF Partners L.P. 3,023,482 7.70 -274,800 3/31/19
Delphi Ventures L.P. 2,426,702 6.18 -- 3/31/19
BlackRock Institutional Trust Company, N.A. 2,368,261 6.04 -22,218 3/31/19
Advanced Technology Ventures 2,110,082 5.38 -- 3/31/19
The Vanguard Group, Inc. 1,597,220 4.07 135,957 3/31/19
Dimensional Fund Advisors, L.P. 1,418,401 3.61 174,355 3/31/19
Adage Capital Management, L.P. 700,000 1.78 -- 3/31/19
State Street Global Advisors (US) 542,648 1.38 8,122 3/31/19

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Federated Kaufmann Fund 2,351,482 5.99 -- 3/31/19
Federated Kaufmann Small Cap Fund 1,352,700 3.45 219,228 3/31/19
Vanguard Total Stock Market Index Fund 890,257 2.27 -- 4/30/19
iShares Russell 2000 ETF 704,611 1.80 -26,260 4/30/19
Vanguard Extended Market Index Fund 537,489 1.37 -4,349 4/30/19
DFA U.S. Targeted Value Portfolio 343,246 0.87 2,112 1/31/19
iShares Russell 2000 Value ETF 286,873 0.73 -10,140 4/30/19
TIAA-CREF Quant Small-Cap Equity Fund 281,127 0.72 -3,100 3/31/19
Wellington Global Healthcare Equity Fund 272,000 0.69 272,000 12/31/17
DFA U.S. Small Cap Portfolio 270,327 0.69 25,369 1/31/19

* Insider values reflect direct beneficial ownership.

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