Media & Investors

Ownership Summary

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Federated Global Investment Management Corp. 6,934,316 12.90 1,449,253 9/30/19
BVF Partners L.P. 6,750,482 12.55 -- 9/30/19
BlackRock Institutional Trust Company, N.A. 3,161,745 5.88 723,485 9/30/19
Delphi Ventures L.P. 2,426,702 4.51 -- 3/31/19
The Vanguard Group, Inc. 2,330,657 4.33 217,468 9/30/19
Advanced Technology Ventures 2,110,082 3.92 -- 3/31/19
Dimensional Fund Advisors, L.P. 1,483,622 2.76 18,451 9/30/19
Adage Capital Management, L.P. 1,300,000 2.42 100,000 9/30/19
Point72 Asset Management, L.P. 1,200,000 2.23 -735,800 9/30/19
Renaissance Technologies LLC 1,078,803 2.01 328,605 9/30/19

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Federated Kaufmann Fund 3,197,902 5.95 846,420 6/30/19
Federated Kaufmann Small Cap Fund 2,200,747 4.09 848,047 6/30/19
Vanguard Total Stock Market Index Fund 1,409,585 2.62 -- 10/31/19
iShares Russell 2000 ETF 1,047,142 1.95 -20,720 10/31/19
Vanguard Extended Market Index Fund 660,428 1.23 -- 10/31/19
iShares Russell 2000 Value ETF 389,150 0.72 -3,289 10/31/19
DFA U.S. Small Cap Portfolio 382,316 0.71 27,909 7/31/19
DFA U.S. Targeted Value Portfolio 349,946 0.65 -- 7/31/19
Wellington Global Healthcare Equity Fund 281,548 0.52 -15,245 8/31/19
TIAA-CREF Quant Small-Cap Equity Fund 272,127 0.51 -1,900 9/30/19

* Insider values reflect direct beneficial ownership.

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